A Review of Deep Learning‑Based Approaches for Detection and Diagnosis of Diverse Classes of Drugs

Artificial intelligence-based drug discovery has gained attention lately since it drastically cuts the time and money needed to produce new treatments. In recent years, a vast quantity of data in various formats has been made accessible in the medical field to analyse different health complications. Drug discovery aims to uncover possible novel medications using a multidisciplinary approach that includes biology, chemistry, and pharmacology. Traditional sentiment analysis methods count or repeat words in a text assigned sentiment ratings by an expert. Several outdated, ineffective old methodologies are utilized to forecast drug design and discovery. However, with the development of DL (deep learning), the traditional drug discovery method has been further simplified. In this work, we applied deep learning models, such as LSTM (Long short-term memory), GRU (Gated recurrent units), Bidirectional LSTM (BiLSTM), Bidirectional GRU(BiGRU), SimpleRNN, embedding+LSTM, embedding+GRU, embedding+GRU+dropout, embedding+conv1d+LSTM, and Embedding+Conv1d+GRU on a dataset of drug reviews. Furthermore, we used Adam and RMSprop, two optimizers, for each model, for increased optimization. This research focuses on categorizing medication reviews into positive and negative categories. The effectiveness of the different deep learning models was assessed using a wide range of performance measures. Experiments demonstrated that the GRU (Gated Recurrent Unit) generated exceptional validation dataset results. In addition, this study emphasizes the relevance of deep learning methods over traditional learning approaches in categorization.

Optimization and Prediction of Karanja oil transesterification with domestic microwave by RSM and ANN

The optimization and transesterification of soybean oil with methanol in the presence of sodium hydroxide as a catalyst was investigated. A low-temperature transesterification process was selected to make the transesterification process more energy efficient. To further improve the production of biodiesel, the experimental design was carried out with the Box-Behnken method. The results were analysed using the response surface methodology. A model was developed to correlate the performance of biodiesel with the parameters of the process, such as the molar ratio, the concentration of the catalyst and the reaction time. The influence of the reaction variables, including; The molar ratio of oil (6: 1–12: 1), temperature (50° C) and catalyst concentration (1–2% by weight) and residence time (30–60 minutes) on the transesterification reaction of the methyl ester of Fatty acid (FAME) were studied. A biodiesel yield of 80.86% with the molar ratio (8:1) was reached using NaOH as catalyst (1.8) in 34 minutes at a temperature of 50° C. It was observed that the catalyst concentration, the reaction time and the molar ratio had a significant effect on the yield of soybean biodiesel.